Grey matter volume differences associated with gender in children with attention-deficit/hyperactivity disorder: A voxel-based morphometry study - U1077 - Neuropsychologie et imagerie de la mémoire humaine
Article Dans Une Revue Developmental Cognitive Neuroscience Année : 2015

Grey matter volume differences associated with gender in children with attention-deficit/hyperactivity disorder: A voxel-based morphometry study

Résumé

Female participants have been underrepresented in previous structural magnetic resonance imaging reports on attention-deficit/hyperactivity disorder (ADHD). In this study, we used optimized voxel-based morphometry to examine grey matter volumes in a sample of 33 never-medicated children with combined-type ADHD and 27 typically developing (TD) children. We found a gender-by-diagnosis interaction effect in the ventral anterior cingulate cortex (ACC), whereby boys with ADHD exhibited reduced volumes compared with TD boys, while girls with ADHD showed increased volumes when compared with TD girls. Considering the key role played by the ventral ACC in emotional regulation, we discuss the potential contribution of these alterations to gender-specific symptoms’ profiles in ADHD.

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Neurosciences
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hal-04389234 , version 1 (05-09-2024)

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Thomas Villemonteix, Stéphane de Brito, Hichem Slama, Martin Kavec, Danielle Balériaux, et al.. Grey matter volume differences associated with gender in children with attention-deficit/hyperactivity disorder: A voxel-based morphometry study. Developmental Cognitive Neuroscience, 2015, 14, pp.32-37. ⟨10.1016/j.dcn.2015.06.001⟩. ⟨hal-04389234⟩
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